Exact(1)
"Eyetech does enjoy a first mover advantage, and while Macugen's peak sales are likely in 2006, we do not expect the drug to go away completely, as the company will continue to explore a combination with Visudyne as well as additional indications," Morgan Stanley said.
Similar(59)
One could consider such observations as the molecular explanation of poor outcomes observed in some cases of PAs, but in light of findings showing gene expression also in normal adult brain astrocytes, such connection should be rather be regarded as additional indication of a gene with a nearly unknown function.
However, continued evaluation in long-term studies and clinical trials is required to evaluate the efficacy and safety of the drug as well as to identify additional indications for its clinical use.
14, 16, 43 Thus, we may expect a similar efficacy and safety with the novel DPP-4 inhibitor, teneligliptin, although this drug requires careful long-term postmarketing surveillance and additional clinical trials to evaluate its efficacy and safety as well as to gain additional indications for its clinical use.
The results revealed lead compounds with activity against clinically important mutant kinases, including ALK, LRRK2, RET, and EGFR, as well as unexpected opportunities for repurposing FDA-approved kinase inhibitors as leads for additional indications.
However, other autoimmune diseases, such as SLE, are additional indications that could be evaluated with this molecule.
Although the models are etiologic by nature and not meant as a predictive tool, the percentage predicted correctly are presented as an additional indication of the model fit.
These findings resulted in a specific change to the SmPC indication for pemetrexed in April 2008 to the second-line treatment of patients with other than predominantly squamous cell histology as well as introducing an additional indication for first-line therapy in combination with cisplatin in this predominantly non-squamous patient group.
Dolgorouki reported all of this to the Tsar as an additional indication of French weakness.
In addition, we analyzed clonality of the Salmonella-specific T cell response using a TCR beta clonality assay, as an additional indication for antigen-specific T cell activation.
As an additional indication, we noticed extreme sequence conservation amongst vertebrates, covering ≈400 million years of evolution.
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