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The Per-Protocol (PP) population was used as a supportive analysis.
Non-parametric methods were also used on the primary efficacy variable as a supportive analysis.
Because the data were skewed, non-parametric methods were also used on the primary efficacy variable as a supportive analysis.
As a supportive analysis, a logistic multivariate model was applied on the composite endpoint for measuring the effect of CRT optimization frequency adjusted for the optimization method used.
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A supportive analysis will investigate any effect of time by including the fixed effect of year.
To explore the robustness of the primary analysis, a supportive analysis of period 1 alone was examined.
Therefore, the full analysis set was added as a supportive sensitivity analysis set to the primary analysis to determine the difference between the two groups.
The same model was applied on the per protocol (PP) population as a supportive efficacy analysis for the aforementioned parameters.
For all pair wise comparisons, the p-values from the primary ANOVA model were compared to those obtained by applying a non-parametric test (Wilcoxon signed rank) as supportive analysis.
A Cox regression model to analyze time to failure was implemented as supportive analysis, which included the mentioned stratification variables and OADs, gender, diabetes duration, HOMA-B, HOMA-IR, baseline A1C, and country.
The FATF report acts as a useful corollary and counterpoint to a recent U.S. State Department report on terrorism around the world, which offered a broadly supportive analysis of Saudi efforts and emphasised the cooperation between Washington and Riyadh.
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