The book can also be used as a textbook or a supplementary reference for an advanced graduate course.
Instead of the textbook being the primary tool used for learning with the lecture as a vehicle, and Web or hard copy references used as a supplementary source of knowledge; the Web is now the primary source of current and relevant knowledge and the book and the lecture becoming secondary.
We next estimated the functional potential of mtDNA synonymous mutations by calculating the difference in CAI values before and after the occurrence of each identified nodal synonymous mutation (i.e., ΔCAI) using CYTB as a reference (supplementary table S5, Supplementary Material online).
We therefore chose the CAI values for the subset of epithelial genes as a reference (supplementary fig. S2, Supplementary Material online).
The number of articles screened by HGMD is increasing on a yearly basis; however, we impose no prior limit upon the number of articles we include as supplementary references for a given mutation.
A Pt/SiO2 catalyst with an average particle size of 1.8 ± 0.6 nm was also prepared as a reference (Supplementary Fig. 8).
Comparable results were obtained using other housekeeping genes as a reference (Supplementary Fig S10).
Model independence of the reconstructions obtained from the respective classes was tested by using the opposite model as a reference (Supplementary Figure S2).
We performed a time-course analysis using lin-42, an mRNA expression of which peaks once during each larval stage (Jeon et al, 1999), as a reference (Supplementary Figure S5B; Materials and methods section).
After removal of the mitochondrial sequences, the remaining reads of the experimental metagenome dataset were analysed (Table 2) using the human genome build 36 version 3 as a reference (Supplementary Table 2).
On the basis of our data, we derived an algorithm, represented in Table 2, with a sensitivity ranging from 80% for TC to 90% for AC, as determined in our sample of 29 carcinoid tumours and assuming the double blind revision as a reference (Supplementary Table 4).
