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The phrase "as a substrate" is correct and usable in written English.
It can be used in scientific or technical contexts, particularly in biology or chemistry, to refer to a surface or material on which a process occurs or an organism grows.
Example: "The bacteria were cultured as a substrate in the laboratory to study their growth patterns."
Alternatives: "as a medium" or "as a base".
Exact(60)
The meshlike material then serves as a substrate that allows internal tissue to grow and resolve the hernia.
In an e-mail, Adamatzky said that, as a substrate for biological computing, plants offered both advantages and disadvantages over slime molds.
Quartz glass was used as a substrate.
Silicon was used as a substrate.
N-type (100) silicon wafer was used as a substrate.
The enzyme activity was examined using pNPG as a substrate.
Stainless steel (SUS304) was used as a substrate.
Silicon is often used as a substrate for column fabrication.
Highly n-doped silicon was used as a substrate.
Neither enzyme showed activity with CH3 H4PteGlu1 as a substrate.
FR4 material is used as a substrate material.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com