Sentence examples for as a structural analogue from inspiring English sources

In this study, we investigated whether pregabalin, an antiepileptic and analgesic drug that is also designed as a structural analogue of γ-aminobutyric acid (GABA), exhibits supraspinal analgesic effects similar to those of gabapentin involving the descending noradrenergic system.

It has been accepted in the biomaterials field as a structural analogue of glycosaminoglycans (GAGs).

The antennal gland of brachyuran crabs can be viewed as a structural analogue of the mammalian nephron (Wheatly, 1985; De Vries et al., 1994; Brown et al., 2009).

In view of these features, it is not surprising that SAHA (harboring the corresponding "metal-binding", "linker", and "cap" regions) serves as a structural analogue of the substrate and thus inhibits enzyme catalysis.

Sulfonamides act as a structural analogue of ρ-amino-benzoic acid and bind dihydropteroate synthase (DHPS), a catalytic enzyme in the folic acid biosynthesis pathway, resulting in the inhibition of dihydrofolic acid formation [ 27].

Inasmuch as bestatin is a structural analogue of a leucyl dipeptide and may be regarded as a transition state mimic, our results imply that the enzyme undergoes induced fit during substrate binding and turnover.

As it is a structural analogue to the amino acid serine, the common designation is serinol.

Using a structure-based strategy, we selected a structural analogue of STA-21 termed as LLL-3, for further evaluation.

In this study, we investigated the inhibitory effects of a small molecule compound known as LLL-3, which is a structural analogue of the earlier reported STAT3 inhibitor, STA-21, on the cell viability of human glioblastoma cells, U87, U373, and U251 expressing constitutively activated STAT3.

Extraction of blood and brain samples was then performed by a method based on protein precipitation using acetonitrile containing a structural analogue of -U50,488 as an internal standard.

Sample extraction was performed by the addition of 400 μl of acetonitrile containing a structural analogue of -U50,488 as internal standard.