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Thus, to date, there have been few studies concentrated on non-CSCs influenced by hypoxia as a sole factor.
Importantly, the main difference between our study and the other studies is that we used LL-37 as a sole factor for monocyte differentiation instead of combining LL-37 with other treatments which may have directed differentiation along another lineages.
However, recombinant CD137 protein as a sole factor is sufficient to induce human monocyte to DC differentiation and these CD137L-DCs are more potent than classical DCs in inducing proliferation, IFN-γ secretion and perforin expression by T cells [20].
Nevertheless the amount of sick notes or the number of days off work may not be taken as a sole factor for the measurement of indirect illness costs.
Taken together, these findings suggest that the possibility of BRCA1/ BRCA2-associated breast cancer should be taken into account with other factors when making decisions regarding radiotherapy and adjuvant chemotherapy, but should not be used as a sole factor to determine the appropriateness of BCT.
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Moreover, in the factor analysis, the scale emerged as a sole component.
His doubts that "the commitment of most Americans to the spreading of freedom and democracy abroad [was] deep enough to sustain strenuous and costly foreign policy enterprises" lead him to dismiss missionary ideology as a sole causative factor (p. 21).
Therefore, it is clear that trans-national diffusion cannot serve as a sole explanatory factor for FRP development; rather, it must be understood as only one piece of the 'explanatory puzzle'.
The question as to whether IZUMO1 is functioning as a sole essential factor in fusion, or rather is participating as a part of protein complex [5], remains unanswered.
The combined analysis of SNPs in IL-15 and other genes may also be needed since the polymorphisms in IL-15 might not serve as a sole risk factor for the disease prognosis.
No patient reported sexual activity as a sole risk factor.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com