The phrase "as a single chain" is correct and usable in written English.
It can be used to describe something that is unified or connected in a continuous manner, often in contexts related to processes, systems, or structures.
Example: "The data was processed as a single chain, ensuring that each step flowed seamlessly into the next."
Alternatives: "in one continuous link" or "as one unified sequence".
The paper, in other words, theorized that the standard, relatively simple view of evolution -- as a single chain of events beginning in Africa -- was wrong in important respects.
The HR1 and HR2 were expressed and purified separately or as a single chain connected by an amino acid linker (HR1-linker-HR2, named 2-Helix).
The fusion protein scFv-tP was constructed as a single chain variable fragment (scFv) against AIV hemaglutinin antigen with a truncated protamine (tP).
SDS PAGE and Edman degradation analysis revealed that frutalin was expressed as a single chain protein since the four amino-acid linker peptide "T-S-S-N", which connects α and β chains, was not cleaved.
To facilitate the solution of the crystal structure of this fusion core, we deployed an Escherichia coli in vitro expression system to express the HR1 and HR2 regions linked together by a flexible linker as a single chain (named 2-helix).
BoNT/A is produced by Clostridium botulinum as a single chain protein that is activated by proteolytic cleavage to form a 50 kDa light chain (LC, 448 amino acids) and a disulfide bond-linked 100 kDa heavy chain (HC, 847 amino acids).
The aim of the work reported in this article was to explore the production of the agglutination assay reagent as both a single chain Fv (scFv) antibody fragment and recombinant full-length mAb, expressed in a secreted form in commonly used mammalian cell lines.
Human vitronectin is a relatively small (75 kDa) glycoprotein that can be secreted as either a single chain or a dimer, is abundant in blood and throughout the ECM and promotes cell adhesion and migration [reviewed by [ 71].
As mentioned above, a single chain was regarded as an independent unit.
TMPRSS6 is produced as a zymogen, a single chain inactive proenzyme, which auto-activates itself by cleavage at an arginine residue at the consensus site RIVGG between the prodomain and the catalytic domain.
The military officers sitting as judges belong to a single chain of command reporting to the secretary of defence and the president, who will designate any accused for trial before the commissions and will also hear any final appeals.
