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To identify 'GC3-rich' and 'GC3-poor' genes with high stringency, we set the P value < 1e−5 as a significant threshold.
However, only the expression fold change observed for the CAD gene (2.17) was higher than the two-fold change conservatively used as a significant threshold in expression studies [ 29].
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With the latest increase in the debt limit, Republicans said, the debt will cross a significant threshold, as it will be roughly the same size as the economy, measured by the gross domestic product.
That is a significant threshold as PCCs in England who want to raise the precept by 2% or more have to hold a referendum - which is what Bedfordshire's PCC, Olly Martins, is doing on general election day.
A significant threshold was defined as a P value of <0.05.
Therefore we selected ± 5% as a clinically significant threshold representing the maximum allowable margin of error.
A q-value of 0.10 was used as a significant association threshold in addition to a more permissive threshold of 0.2.
Using P<0.001 as a significance threshold, a number of significant associations were detected for all four traits (Table 1).
A DREM diverging score less than 0.1 was used as a significant score threshold for TF-grouped gene relationship.
Bonferroni's adjustment was applied to the significance thresholds, and a P value of <0.008 was adopted as the significant threshold (Table 2).
Among patients with type 2 diabetes mellitus, a stepwise approach identified 8.6 mmol/L glucose concentration as the significant threshold of risk increase (aOR 1.63, 95% CI 1.07 2.48; p = 0.02).
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