Sentence examples for as a significant expression from inspiring English sources

In the HepG2 cells induction of this gene was detected by RTqPCR but was not identified as a significant expression change on the microarrays.

Of these criteria matches four were related to the anatomical site of expression (pinpointing the brain as a significant expression location of this gene) and the other two were related to phenotype similarity in the mouse.

We found that WP1066, a specific JAK/STAT3 inhibitor, as well as sorafenib can induce a significant expression level of LC3-II, and that, ectopic expression of STAT3 can further restore sorafenib-induced autophagy, which indicates that inhibition of p-STAT3 has a vital role in autophagic activity.

We defined as candidate informative genes those with unadjusted P<0.05, and as differentially expressed genes those with a significant expression difference (adjusted for multiplicity P<0.05).

However, as previously noted, the gills showed a significant expression of some immune-related molecules, such as the PIF protein, perlucin, LPS binding protein, big defensin or apextrin, which displayed fold changes ranging from 1243, in the case of apextrin, to 2837, in the case of PIF.

It would therefore be necessary to improve its function in order to use this fragment as a significant gene expression tool in non-Lepidopteran insects.

Liver expression analyses provided supporting evidence for the predicted interaction between FHL2 and WNT4, as a significant co-expression (r = 0.44, P < 0.001) was observed.

In the resistant strain, the cadherin gene displayed patterns of nucleotide polymorphisms consistent with the action of positive selection (e.g. an excess of high compared to intermediate frequency mutations), as well as a significant under-expression compared to the susceptible strain.

Comparisons of mRNA expressions of cell cycle genes, made between, 1) normal liver to early HCV and 2) early HCV to advanced HCV, revealed that fifteen (18%) of the 84 cell cycle genes were not detectable in any of the comparative groups, when Ct value greater than 35 was applied as a cutoff for significant expression.

A normalized relative Cy5/Cy3 ratio >2 was considered as a significant increase in expression and a normalized relative Cy3/Cy5 ratio >2 was considered as a significant decrease in expression.

A twofold difference was interpreted as a significant difference in expression between the parental and the mutant strains.