The phrase "as a significant cause" is correct and usable in written English.
It can be used when discussing the reasons or factors contributing to a particular outcome or event.
Example: "The study identified climate change as a significant cause of the increase in extreme weather events."
Alternatives: "as a major factor" or "as a key reason".
Research by water utility Anglian Water revealed the disposal of "unflushable" sanitary pads as a significant cause of the problem.
In recent years, traumatic brain injury (TBI) has been identified as a significant cause of growth hormone deficiency (GHD).
Grid-to-rod fretting damage remains as a significant cause of nuclear fuel failure in pressurized water reactors (PWRs).
Environmental noise, especially that caused by transportation means, is viewed as a significant cause of sleep disturbances.
8.27pm: The industry reaction in the US appears to pick out BP's focus on the cement used in the well as a significant cause of the blow-out.
In "Charge More, Merge Less, Fly Better" (Op-Ed, April 21), Robert Crandall describes airline service as "unacceptable" and cites deregulation as a significant cause.
Diarrhoeal diseases, linked to poor hand washing and hygiene practices, as well as inadequate sanitation, are a significant cause of death among children under five in Afghanistan.
The Food and Drug Administration says the drugs, known as fluoroquinolones, are a "significant cause" of human infections by resistant camplyobacter bacteria, contracted primarily by eating chicken.
Diabetes presents a serious health challenge, as it is a significant cause of ill health and premature death.
Among other conditions, they most frequently and empathetically stated urinary incontinence and care related to that condition as being humiliating and a significant cause of sadness.
With longer follow-up, other causes such as malignancy, appear to become a significant cause of mortality.
