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The use of CAD as a second reading increased cancer detection by 15% [ 21].
More studies are necessary to evaluate the use of CAD as a second reading and to assess its impact on the reader's capability not only to detect emboli but also to exclude pulmonary embolism.
While an NPV of 92% is not yet sufficient for complete reliance on a negative CAD reading, it underlines the potential role of CAD as a second reading to reassure a reader when excluding PE.
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As a second read-out of filopodia stability, the average velocity of MYO10 spots was measured and was found to be much higher in CCB-treated cells indicative of faster filopodia turnover following L-type calcium channel inhibition (Fig. 4e).
Melatonin-promoted activation of the ERK1/2 pathway was used as a second read-out to determine the signaling properties of melatonin receptor mutants.
Small wonder that David Mitchell advocated a second reading – as does the author himself.
Noah Bean, who felt that he gave "an awful first audition" for the role of David, was called in for a second reading as he was waiting for an elevator to leave the building, and was ultimately cast.
Additionally, orf61 of Sf101 phage lies inside orf60, in a second reading frame, as in other lamdoid phages [ 38].
In accordance with PSAWG2 criteria (Scher et al, 2008), a PSA decline was defined as confirmed if it presisted in a second reading at least 3 weeks later.
Painful as a first reading may be, it doesn't compare with the possibilities for the program following.
This obviously places wide limits on permissible conduct, though it isn't as chilling as a first reading might suggest, for the necessity requirement can be hard to meet.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com