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Recently, the p38 MAPK was identified as a required factor optimizing CAR activation and CYP2B6 induction in liver cells (Saito et al., 2013).
In fact, PDL-1, the endogenous ligand of PD-1, has been demonstrated as a required factor for peripheral transplantation tolerance and protection aganist chronic allograft rejection [ 30].
Moreover, a study using shRNA library targeting 243 known chromatin regulators identified Brd4 as a required factor for the maintenance of acute myeloid leukemia (AML).
Ubiquitination of Smad4 is known to be a key regulatory step in the TGF-β signaling pathway, leading to the identification of the DUB USP9X as a required factor for Smad activity [ 30, 32, 37].
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The change in swelling degree (Q) suggested the presence of a conformational memory of the hydrogel that might allow the design of stimuli-response but also tailored-made hydrogels responding at a required factor as temperature.
Inositol has not been established as an essential nutrient for humans; however, it is a required factor for the growth of some yeasts and fungi.
We introduce quiz taking as a required component of the lecture grade to decrease this self-selection factor.
Our findings identify YAP as a required signaling factor through which fibrous substrate topography influences cell behavior and highlights topography as a key design parameter for engineered biomaterials.
The NFκB is a required transcription factor for canonical IL-1 target genes expression.
Keep the foreign language requirement in and add computer science as a required course.
The aim was to introduce safety for journalists as a required course in their respective curricula.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com