Sentence examples for as a relevant endpoint from inspiring English sources

G-BA agreed with the manufacturer and acknowledged GFR as a relevant endpoint.

Moreover, the absence of progression of disease is increasingly considered as a relevant endpoint for clinical trials, replacing response rate[ 5, 29 ].

The quality of life of patients with cancer has been identified as a relevant endpoint in research and clinical practice [ 28].

However, currently it is not used as a key endpoint by regulatory agencies, since it has only recently been confirmed as a relevant endpoint, and there are few exposure/response studies available.

Furthermore, as mentioned, AKI, as defined by serum creatinine changes, is a relevant endpoint because it is strongly associated with increased mortality and morbidity.

In clinical trials, hospitalisation is a relevant endpoint in itself, as it provides a direct measure of costs associated with AF; however, it is also a relevant surrogate endpoint for death.

7. We suggest that indication of RRT should be defined within a study protocol in advance in future studies, when RTT is used as a relevant study endpoint.

In this respect, we believe, as far as 'need for RRT' is used as a relevant study endpoint, a standardised study protocol clarifying mode, dose, type of anticoagulation and rules for starting and stopping of RRT are mandatory.

The association between PFS and HRQoL reported here supports the use of PFS as a primary endpoint in clinical trials in patients with NSCLC, as it confirms the value of PFS as a patient-relevant endpoint associated with tangible improvements in HRQoL.

Although IQWiG considered SVR irrelevant, G-BA decided to accept SVR as a patient-relevant endpoint, demonstrating inconsistency in the interpretation for patient relevance.

These small-scale studies are designed to detect a signal that the drug is active on a pathophysiologically relevant mechanism, as well as preliminary evidence of efficacy in a clinically relevant endpoint.