The phrase "as a reference panel" is correct and usable in written English.
It can be used when referring to a group or committee that provides guidance, feedback, or expertise on a specific topic or project.
Example: "The research team consulted with experts in the field, inviting them to serve as a reference panel for their study."
Alternatives: "as an advisory group" or "as a consultative panel".
(e) Accuracy and percentage of missing genotypes for SNP imputation over a range of imputation thresholds, considering the 80 genomes as a reference panel (3,184 SNPs with <10% missing data) and 216,000 tag SNPs in test accessions.
To do this, data from unphased Hapmap phase II CEU (USA residents of northern and western European ancestry) individuals (release 24, build 36, forward strand) was used as a reference panel.
Seven microsatellites (TCM1-7) showed no amplification with T. brucei or T. vivax DNA, but polymorphic amplified products were detected in all of the T. congolense Savannah subgroup used as a reference panel (14 isolates from seven countries).
Ninety-two additional samples were provided as a reference panel.
Data from the 1000 Genomes Project (47) (Phase I interim data, released June 2011) were used as a reference panel.
Are the HapMap SNPs able to act as a reference panel and show concordance to other close populations?
Let ∑ G be the correlation matrix of SNP genotypes, e.g. as estimated from a reference panel, U be the vector of weighted sum of Z-scores by category (i.e. the synthetic scores) and ∑ U be the variance covariance/correlation matrix of U.
As discussed below, if a reference panel had been available for imputation, then there would have been many more opportunities for gains in power from MI.
We constructed a reference panel as described elsewhere (Brown et al. 2012; Fjell et al. 2012; Walhovd et al. 2012).
As shown in the results, combining a reference panel with a reasonable sample size and the combined data genotype panel is a cost-effective approach to increasing imputation quality of rare variants.
Approaches that rely on observed multimarker genotypes to construct tests at untyped SNPs have a close relationship to imputation-based approaches, relying on a reference panel (such as HapMap or 1000 Genomes) to infer information at untyped SNPs on the basis of their correlation pattern (in the reference panel) with genotyped SNPs.
