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Functionally, this manifests itself as a reduction in the capacity of layer 2/3 to elicit subthreshold activity in the deprived cortical areas.
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They fear a reduction in the capacity available to freight.
Concurrent with this increase in fibrosis, the regenerative capacity in muscle declines, which may reflect a reduction in the numbers of Pax7+ myogenic cells in the muscle (satellite cells) that are necessary for continued myogenesis (Shefer et al., 2006), as well as a reduction in the myogenic capacity of aged satellite cells (Schultz & Lipton, 1982; Chakravarthy et al., 2000).
The upshot is a slew of languorous individual connections, as well as a reduction in the channel's capacity to handle the maximum number of users.
There is considerable decrease in dermal thickness and vascularity as well as a reduction in the number and biosynthetic capacity of the fibroblast resulting in delayed wound healing.
The lack of improvement in these groups may be due to a reduction in the residual functional capacity as a result of the four-hour ventilation without PEEP.
As for the pathophysiological mechanisms leading to such an imbalance, although a partial and/or local reduction of blood supply is likely, a reduction in the muscle oxidative capacity itself or a combination of both cannot be discarded.
Another mechanism proposed as a result of CASQ2 mutations is a reduction in the amount of CSQ2 or in the calcium-binding capacity of the mutant CSQ2.
Considering this interference or noise as independent from the signal leads to a first reduction in the capacity of system (8) w.r.t. the true system (7).
(The Commission also warned presciently that "rapidly growing demand combined with a reduction in capacity, as the result of continued reliance on outdated equipment, will bring our nation's aviation system to gridlock soon after the turn of the century").
Secondly, there is a reduction in reservoir capacity as well as degradation of downstream water quality.
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