The phrase "as a random coil" is correct and usable in written English.
It can be used in scientific or technical contexts, particularly in discussions about molecular biology or biophysics, to describe the conformation of a polymer or protein.
Example: "The protein unfolded and assumed a structure that can be described as a random coil, lacking any defined secondary or tertiary structure."
Alternatives: "in a disordered state" or "as an unstructured chain".
Circular dichroism spectroscopy shows that the apopeptide exists as a random coil and assembles into a coiled-coil in the presence of Cd2+.
The high affinity for Zn II) was mainly due to a high effective concentration of the fluorescent proteins and could be understood quantitatively by modeling the peptide linker between the fluorescent proteins as a random coil.
The circular dichroism studies reveal that the peptide exists as a random coil in solution but folds into a less ordered conformation upon binding to POPC/POPG (3:1) vesicles.
Furthermore, several conformations selected from the unfolding process are studied to show that the denatured state does not behave as a random coil, but seems to have highly cooperative motions, which may help and promote the polypeptide chain to fold into the native state correctly and speedily.
The ssDNA thus behaves as a random coil.
In an aqueous environment sPB1-F2 is mostly present as a random coil peptide.
More surprisingly, we also find that the KSV values of the oligomers are similar, within experimental error, to those of monomeric Aβ implying that Tyr10 is exposed to a similar extent as in a random coil monomer.
Before binding to ANK repeats, AS adopts a random coil structure as indicated by its NMR spectrum (data not shown).
AS adopts a random coil conformation according to a maximum degree of negative ellipticity at about 198 nm.
With the exception of the study reported by Qiu et al., all previous T-jump studies of Trp-cage dynamics have relied on the disappearance of helical amide I′ bands, either monitored directly or as the appearance of a random coil amide absorbance.
In its purest sense, gelatine can be defined as a polypeptide chain in a random coil configuration.
