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"Diet can serve as a protective function," says Sandquist.
The sensation of pain serves as a protective function, by alerting us to real or impending injury, triggering protective responses [1].
Given the above information, we speculated that PPAR α activation may serve as a protective function to restrain liver inflammation in cases of ALF.
Dehaloperoxidase hemoglobin A (DHP A) is a multifunctional hemoglobin that appears to have evolved oxidative pathways for the degradation of xenobiotics as a protective function that complements the oxygen transport function.
This distribution in normal tissues resembles the distribution of Pgp (Ambudkar et al, 1999) and may point towards a physiological role comparable to Pgp, such as a protective function in normal tissues and fetus against toxic agents, regulation of uptake of orally administered substrates, and excretion processes in the liver.
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Studies by other researchers also confirmed that several E3 ubiquitin ligases (such as Parkin) exhibit a protective function against ER stress-induced apoptosis in neuronal cells [ 26].
It should be noted that this biological function can be regarded as the opposite of a protective function against chitinases that was reported for other fungal LysM effector proteins.
In addition, both GLP-1 receptor agonists and insulin analogs, such as insulin glargine, exhibit a protective function on beta cells, suggesting that the two agents in combination might represent a new therapeutic option for preservation of beta cell mass in patients with type 2 diabetes.
This is consistent with the findings that the induction of GRPs causes a protective function as the survival responses to nutrient starvation, acidosis, and hypoxia conditions, which are common in poorly vascularized solid tumors [11], [40].
The same may be true in the esophagus after the reflux of an excessive amount of gastric acid, and PGs may act as a mediator of such a protective function in this tissue, in collaboration of these afferent neurons.
It has been suggested that a dampening of stress responsivity during pregnancy, may serve a protective function, as over exposure to maternal stress hormones and alterations in cardiovascular responses, including uterine blood flow, may disrupt normal fetal development (Christian 2012).
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