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Transcription factor Sp1, an important and well-studied DNA binding protein, was used as a proof example and immobilized onto a glass carbon electrode (GCE) surface, with the wild type Sp1 consensus binding sequence (wtDNA) and a mutant sequence carrying two point mutations (mutDNA) within the Sp1 binding site served as testing samples.
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I don't spend a lot of time playing games myself, but it's really cool as a first proof example of an industry that's getting completely disrupted by the whole social movement.
The fitting of the selected nephroblastoma case to the clinical data serves as a proof of principle example, demonstrating the basic philosophy of a possible procedure towards the selection of prevailing virtual scenarios, based on the combined use of the available multiscale clinical and literature data.
As a proof of concept example, the method was first applied to the Sears et al. carnivoran dataset [ 13].
A simply supported RC slab was constructed and used as a proof-of-concept example.
Pyrococcus furiosus DNA polymerase (Pfu Pol) was employed as a proof-of-principle example.
Here we present the direct evidence and enhancement of SPR effect using TiO2 nanotube arrays (TNTAs) loaded with Ag nanoparticles (NPs) as a proof-of-concept example.
Although we use Auckland as a proof-of-concept example, the method may be adapted for any city exposed to a tephra hazard.
The first species investigated was E. coli, which should serve as a proof-of-principle example that the Real Time PCR method developed for haloarchaea [21], which can be lysed very gently and efficiently by osmotic shock, can also be applied to gram-negative bacteria with a much more rigid cell envelope.
We further chose KIT as a proof-of-principle example as the confirmed association between KIT duplication and MCH and MCV.
This work serves as a proof-of-concept example on how trial design and decision making in oncology can be further informed using a model-based approach in early clinical drug development.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com