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In addition, transgenic gentian plants using promoters other than 35Spro showed stable transgene expression [11], [14], implying that the 35Spro sequence acts as a possible inducer of cytosine methylation in gentian.
We also identified TNFα as a possible inducer of CRP expression in the mouse cell line 3T3-L1.
Consequently, we asked ourselves whether the loss of coronary microvascular DPP4 after AMI relates to the endothelial phenotype shift towards a more pro-coagulant state and the induction of situ thrombosis as a possible inducer of MVO after AMI.
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Even though for cellohexaose, that was selected in our study, there are no reports for acting as a possible enzyme inducer, other cello-oligosaccharides (cellotriose, cellotetraose and cellopentaose) were investigated as inducers of the genes encoding cellobiohydrolases by Suzuki et al [ 15].
We thus explored IL-1α as a possible SASP inducer in the monocytes.
Elhaik E, Zandi P. Dysregulation of the NF-kappa B pathway as a potential inducer of bipolar disorder.
Sophorose is the strongest cellulase inducer and is considered to be a possible natural inducer.
Food, microbiota and bile acids have been discussed as possible inducers of low-grade inflammation and impaired permeability in IBS.
The serendipitous discovery of vitamin C as an inducer of the M. tb DevR regulon is novel as it implicates an essential nutrient as a possible stimulus for the first time.
This suggests that TNF is not the main inducer of extranuclear HMGB1 during synovitis and that HMGB1 may represent a TNF-independent molecule that could be considered as a possible target for future therapeutic intervention in RA.
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