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This strain was originally isolated from human saliva and is used as a model microbe in the study of host-microbe interactions, due to its established taxonomy, its ability to survive gastrointestinal (GI) transit [ 8] and its putative role as a probiotic species [ 9].
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Furthermore, the mechanism of the improved aerobic biodegradation using Al-ORABs under oxygen-limiting groundwater conditions was elucidated in batch and column studies with 1,4-dioxane and Mycrobacterium sp. PH-06 as a model contaminant and aerobic microbes, respectively.
In addition, it underscores the value of C. elegans as a model to study host-microbe interactions.
Zymosan, a glucan with repeating glucose units connected by β-1,3-glycosidic linkages, induces inflammatory signals in macrophages through toll-like receptors TLR2 and TLR6 and has served as a model for recognition of microbes by the innate immune system for over 50 years [ 42].
Biology 44Y, an IBI prize-winning module, helps students do science by practice, with a focus on plant-pollinator-microbe interactions as a model system.
This is a well studied agronomically important process that is also used as a model to study general genetic aspects of plant-microbe interactions [ 1, 2].
Here we have investigated host-pathogen cross-talk by profiling global gene expression over a time course in both the host cell and the microbe simultaneously, using M. tuberculosis-infected human Mφs and DCs as a model system.
Leu-AMC is a commonly used aminopeptidase substrate for diverse environmental microbes (Hoppe et al., 2002) and has served as a model for general proteolytic activity.
Medicago truncatula (barrel medic) has been chosen as a model plant for the Fabaceae family, primarily to study relationships between plants and their symbiotic microbes.
Ferulic acid was chosen as a model lignocellulosic biomass-derived compound for this study because it has detrimental effects on fermentative microbes even when present at a small concentration [ 2, 3].
Drosophila melanogaster has circulating macrophages that phagocytose microbes similarly to mammalian macrophages, suggesting that insect macrophages can be used as a model to study cell-mediated innate immunity.
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