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At about the same time the Texas senator sent out his incendiary tweet, Donald Trump, the Republican frontrunner, tweeted out a message describing Scalia's death as "a massive setback for the Conservative movement and our COUNTRY!," but, at least at first, he didn't say anything about preventing President Obama from naming a replacement.
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Salford's hopes of a top eight finish in Super League suffered a massive setback as Widnes ran in eight tries in an emphatic win.
The latest earthquake is a massive setback for the Nepal as the the impoverished mountainous nation tries to rebuild following April's tragic earthquake that killed more than 8000 people.
"Losing our captain is a massive setback, Jean has been superb as our leader on and off the field," said Springbok coach Heyneke Meyer.
Even as details emerge of what went wrong, this is clearly a massive setback to a company hoping to pioneer a new industry of space tourism.
Marois announced her resignation on Monday night, with which Quebec's separatist movement was handed a massive setback.
But I was highly disappointed with some of these character traits, and these were a massive setback for me.
If, however, they had visions of posting a defendable total and then throttling England they received a massive setback at the start of their innings.
The BBC's Ahmed Maher says the offensive is a "massive setback" for the government.
In the response, Aereo calls this decision a "massive setback for the American consumer".
Today's decision by the United States Supreme Court is a massive setback for the American consumer.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com