Sentence examples for as a major pathogenic from inspiring English sources

Immunological dysregulation is now recognised as a major pathogenic event in sepsis.

Immunoparalysis has been convincingly established as a major pathogenic mechanism in sepsis (Hotchkiss et al, 2013).

HBx has been suggested as a major pathogenic protein for HBV-associated HCC.

These findings further support the concept of oxidative stress as a major pathogenic factor in initial multiple sclerosis lesions (Lassmann and van Horssen, 2011).

The role played by IgE in AD is unclear, with limited data to support this molecule as a major pathogenic effector.

Glutamate excitotoxicity has been implicated as a major pathogenic process in many neurodegenerative conditions, including AD (Alzheimer's disease), motor-neuron disease and following traumatic brain injury (Arundine and Tymianski, 2004; Hynd et al., 2004).

The DV non-structural protein 1 (NS1) may also play a major pathogenic role, as it interacts with host complement proteins [ 11, 12].

Oxidative stress is believed to play a major pathogenic role in retinal degeneration as found in diabetic retinopathy and AMD.

Undesired activation of the complement system, a part of the immune system, is a major pathogenic factor contributing to various diseases, such as ischemia-reperfusion injury, sepsis, asthma, allergic reactions, rheumatoid arthritis, Alzheimer's disease, myasthenia, multiple sclerosis and others.

Oxidative stress is a major pathogenic mechanism of lead neurotoxicity.

Cardiomyocyte loss is a major pathogenic mechanism leading to heart failure.