The phrase "as a major effect" is correct and usable in written English.
It can be used to indicate a significant outcome or consequence of a particular action or event.
Example: "The new policy was implemented, and as a major effect, employee productivity increased significantly."
Alternatives: "as a significant consequence" or "as a primary outcome."
It was considered as a major effect QTL when its LOD score was larger than 2.5.
Special effects producer Mike Tucker was reminded of the James Bond film The Man with the Golden Gun when reading the scene in which the Nestene's lair is blown up, and sought to display it as a major effect.
The hypothesis that susceptibility alleles for ESRD have higher frequencies in West African than European gene pools led to the identification of the Apolipoprotein L1 gene (APOL1) as a major effect gene [ 2].
Thus, the maternal biases found in many of the significant transcripts in this study may also be explained by mito-nuclear incompatibilities between Africanized and European honey bee strains; therefore, we cannot rule this out as a major effect on gene expression.
Previous work reported by Tijsterman et al. (2002) and Elvin et al. (2011) identified ppw-1 as a major effect gene in RNAi sensitivity variation between N2 and CB4856, and also found F2 and recombinant inbred line evidence supporting complexity in the trait.
Interestingly, the authors chose to report the 5%to6%6% rate of those affected with breast cancer testing negative (phenocopies) from a Dutch prospective analysis as a reason to dismiss the phenocopy rate as having a major effect in their analysis [ 3].
One QTL, which was detected as having a major effect on both RDS and RDSA, was mapped near SNP marker P0684 on the long arm of chromosome 1 (Figure 5, Additional file 6: Figure S3).
Thermal inertia, as well as heat losses, had a major effect on the dynamic behavior of the actuator.
The spleen appears to have a dual role in malaria infections as it destroys pRBCs but also appears to modulate parasite biology as splenectomy has a major effect on the parasite phenotype (Engwerda et al., 2005).
Mr. Browne said southern Manhattan always dwarfs other areas of the city in generating complaints of grand larceny, "so it should not come as a surprise that a decrease there would have a major effect, as would an increase".
The earthquake that hit Japan earlier this year has a lot to do with the slump, as it had a major effect on the company's supply chain.
