The phrase "as a major challenge in the" is correct and usable in written English.
It can be used when discussing significant difficulties or obstacles within a specific context or field.
Example: "Climate change is often cited as a major challenge in the fight for environmental sustainability."
Alternatives: "as a significant obstacle in the" or "as a key issue in the".
Thus data pretreatment, or normalisation, has been recognised as a major challenge in the analysis of microarray data.
As mentioned earlier in this paper, the County Government of West Pokot in its County Integrated Development Plan 2013 to 2017 identifies gender inequality as a major challenge in the county.
Nowadays, this B2C distribution of parcels accounts for 56% of all shipments in e-commerce [1] and, thus, B2C e-commerce has been identified as a major challenge in the urban logistics literature [2, 3, 4, 5, 6].
The County Government of West Pokot in its County Integrated Development Plan (CIDP) 2013 to 2017 identifies gender inequality as a major challenge in the county, reiterating that most women are confined to household/domestic chores and are mostly not involved in decision-making committees (County Government of West Pokot 2013).
A 2012 Australian study of people with psychotic disorders found that 43 % of participants cited financial problems as a major challenge in the coming year [ 6].
Several other laws of the apartheid era (e.g. the Group Areas Act No. 41, of 1950; the Bantu Education Act No.47 of 1953 and the Industrial Conciliation Act No. 28 of 1956) marginalized Black Africans from meaningful economic participation, and set in motion the racially and geographically defined wealth inequalities that persist as a major challenge in the country [ 27].
Thus, relieving the product inhibition is a major challenge in the process, as well as in enzyme engineering [ 6].
Severe pneumonia is a major challenge in the Intensive Care Unit, as it is characterized by high morbidity and mortality.
Exposure assessment was also a major challenge in the studies.
Lack of resources was seen as a major challenge in several of the schools.
The long latency of TB is frequently observed as a major challenge in constructing epidemiological models for TB [ 16].
