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The phrase "as a leading indication" is correct and usable in written English.
It can be used when referring to a primary signal or sign that suggests a particular trend or outcome.
Example: "The increase in consumer spending serves as a leading indication of economic growth."
Alternatives: "as a primary indicator" or "as a key signal".
Similar(60)
Uterine fibroids can severely impact a woman's quality of life, result in significant morbidity and are a leading indication for hysterectomy.
Protein families identify phylogenetic groups of proteins sequences that are a leading indication of functional analogy.
Chronic infection with HCV is a leading indication for liver transplantation [ 19].
Despite being a rather rare cause of cirrhosis, PBC represent a leading indication for liver transplantation [42].
Moshfeghi et al. conducted a review of enucleation and reported trauma as the leading indication for enucleation worldwide and for 40.9 % of cases in the United States, [ 24] and trauma has been the leading cause for both types of anophthalmic surgeries in some reports [ 10, 25– 29].
Because of recent changes in allocation algorithms, IPF has emerged as the leading indication, accounting for one-third of lung transplant cases [ 1], [ 3]–[ 7].
The main indication for caesarean section in this study was fetal distress whereas dystocia was the leading indication in a study done in Iraq [ 9].
In 621 patients, trauma was the leading indication for the procedure, with a success rate of 99.1%.
Dilated cardiomyopathy is an important cause of heart failure and the leading indication for cardiac transplantation worldwide [ 14].
Fetal indications ranged from 9.4%too 27.2%; the leading indication was "fetal compromise"; we did not collect additional information from the patient file, such as fetal heart rate, to validate the fetal compromise indication.
The leading indication for primary cesarean is dystocia [ 6].
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com