The phrase "as a large increase" is correct and usable in written English.
It can be used when discussing a significant rise or growth in a particular context, such as statistics, economics, or any measurable data.
Example: "The company reported as a large increase in sales this quarter, indicating a positive trend in consumer demand."
Alternatives: "as a significant rise" or "as a substantial growth".
The weakening of this protective umbrella has had direct implications, such as a large increase in skin cancer in Australia.
Most experts agree that it would be difficult for Japan to permanently close all of its 54 plants without substantial fuel costs, as well as a large increase in carbon emissions.
It would also clean up expected problems in social security and Medicare by fixing a shortfall looming next year in social security payments to the disabled, as well as a large increase in Medicare premiums and deductibles for doctors' visits and other outpatient care.
The results from the baseline approach are based on regressions that ignore "reverse" reforms, which can be defined as a large increase in the benefit replacement rate.
The arrival time is at 06.25 UT, a slight increase in power of the first detail around 06.25 UT can be recognized where as a large increase in the power of the second and third details around 06.25 UT is detected.
China is undergoing massive and rapid socio-economic changes leading to environment and population health challenges such as a large increase in non-communicable diseases, the emergence and re-emergence of infectious diseases, new health risks associated with environmental pollutants and escalating health inequality.
As well as noticing a large increase in arrears, all the pilot projects have seen increases in the costs of getting the rent from the tenants.
Participants separately reported their level of moderate activity, defined as causing a small increase in breathing or heart rate with examples of brisk walking, bicycling, vacuuming, and gardening, and vigorous activity, defined as causing a large increase in breathing or heart rate with examples of running, aerobics, and heavy yard work.
Efficient repositioning of nucleosomes by RSC was dependent on ATP hydrolysis, as observed by a large increase in end-positioned nucleosomes at the expense of centrally positioned nucleosomes (Figure 2B, compare categories 1 3 with 6 and 7).
Importantly, the O2.− sensor MitoSox oscillated out of phase with the yeast autofluorescence (Fig. 6B) as expected from a large increase in ROS production and release from mitochondria after NAD(P H oxidation, in phase with ΔΨm depolarization [47].
In the monomeric form (i.e. at pH 5.8), the MQP insertions leads to more disorder in the secondary structure of the chimeric protein as indicated by a large increase in CD intensity at 202 nm.
