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In considering the developmental origins of health, puberty, as well as fetal and early life, should be considered as a key developmental window, with potentially life-long effects on health.
Early childhood is recognised as a key developmental phase with implications for social, academic, health and wellbeing outcomes in later childhood and indeed throughout the adult lifespan.
Early childhood is recognised as a key developmental period in which to address the obesity epidemic [ 6, 7] and UK health policy endorses this [ 8- 10].
A transient histone deacetylation event occurs during seed germination one day after imbibition, and serves as a key developmental signal that affects the repression of a number of histone deacetylase regulated genes [ 67].
At each flowering time QTL, early flowering correlated with fewer vegetative phytomeres, indicating the latter as a key developmental strategy to adapt the maize crop from the original tropical environment to the northern border of the temperate zone (southern Canada), where Gaspé Flint was originally cultivated.
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The most well characterized of the SET1 proteins is MLL1 (hereinafter referred to as MLL), a key developmental protein that sustains the expression of selected target Hox genes required for proper embryonic development including the haemopoietic system [ 4], myogenesis [ 5] and neurogenesis [ 6].
Thus, failure to down-regulate these Th2 response-associated genes, e.g., Clca3, Chi3l3, and Chi3l4, in the PND 10 42 interval is a key developmental shift that occurs as a consequence of Scnn1b-Tg expression.
What follows is a key developmental period for the foetus.
Germination is a key developmental stage in plant life cycle.
Hedgehog (Hh) signaling is a key developmental pathway.
The Gcm protein is structurally conserved, as are most key developmental factors present in the fly genome.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com