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Further evidence for genetic effects comes from examining the fitness of wild-born, adult fish as a function of the ancestry of their parents.
(A ) Pause-free velocities of the wild-type Pol II on bare DNA (black) and nucleosomal DNA (red) are plotted as a function of the transcript length.
Second, we estimate the curve r a as a function of OD (Eq. 3) using data from the wild-type strain, and generate sample r a functions to determine how errors in measuring r a affect estimates of mean fluorescence.
Mean (±SEM) fold change in Glast expression for Clock/Clock astrocytes was calculated using the ΔΔCt (deltadeltaCt) method and expressed as a function of wild-type values.
GAP-stimulated hydrolysis is plotted as a function of GAP concentration for wild type and switch II glutamine mutant Rabs.
Figure 3 illustrates the composite changes in chemical shift (δNH) upon G3P binding as a function of residue number in wild-type cTIM and the L6RM.
Dominant-negative TP53 mutations are frequently described as very strong, completely abolishing the function of the wild-type protein [ 6].
The voltage dependence of activation was determined as a function of voltage and compared to wild type (Fig. 3B).
And as geneticists we focus on null or strong loss-of-function mutations, as these typically provide the most easily interpretable information about the function of the wild-type gene.
We found that the degree of melanism increased steeply in the wild as a function of latitude.
A previous study has indicated that the ΔFHA mutant of CHFR acts as a dominant-negative and can disrupt the checkpoint function of the wild type protein [1].
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