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Heritability estimates and the rMZ for the response of an intervention (based on change scores) are commonly reported in studies where twin pairs are considered as clusters, with the treatment effect as a fixed variable [22].
Therefore, we also included a generalized linear model with family as a fixed variable only.
Firstly, the Charlson Index score was analyzed as a fixed variable determined at the start of follow up.
Treatment received in this period was defined as baseline treatment and used as a fixed variable in the analyses.
The correlation matrix revealed strong multicollinearity (data not shown), especially for the variable "region", which was then included as a fixed variable in the regression model.
As judged by the AIC, the best model for explaining the infection success was model Cops.m5 (Table 3), including family only, as a fixed variable.
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During analysis, patient data were fitted as a random variable with the time as the fixed variable.
For each cell, a one-way ANCOVA was performed between different journeys within a given subtask or between different task-demands within a journey as independent (fixed) variables, firing rate as the dependent measure, and with running speed, head direction and lateral position as covariates (R version 2.15.2; The R Project for Statistical Computing, Vienna, Austria).
In this analysis, BMI percentiles at baseline and 12 months will be used as a repeated variable, intervention group will be used as a fixed subject variable, and maternal and family characteristics will be covariates (first individually and then jointly) to examine how they relate to changes in weight across the sample.
Using an ANOVA model with untransformed data (the means for each pot), with continent and treatment as fixed variables and site as a random variable, only the effect of -catechin treatment was significant for emergence (F = 64.12; df = 1,54; P = 0.004) and for height (F = 32.55; df = 1,40; P = 0.0011).
A logistic regression mixed model was fitted to test which factors influenced survival of the EB treatment, with exposure time, gender of individuals and experimental group as fixed variables and family as a random factor.
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