The phrase "as a first pathway" is correct and usable in written English.
It can be used to indicate an initial option or method for achieving a goal or solving a problem.
Example: "As a first pathway, we should consider implementing a new marketing strategy to increase our outreach."
Alternatives: "as an initial approach" or "as a primary route".
Therefore, it is possible that direct inhibition as a second pathway to reduce Dsg 3 binding in PV may explain the more severe phenotype of PV.
Studies in human cell line models of ATD first led to the recognition that autophagy was activated by intracellular accumulation of ATZ, and later it was shown that autophagy participated as a second pathway for disposal of mutant ATZ [ 14, 15].
A particular form of this metabolism is H2-dependent methylotrophic methanogenesis, which may be referred to as a fourth pathway (Welander and Metcalf 2005), where all the methyl-S-CoM is reduced into methane, the electrons being obtained from H2 coming from an external source (fig. 1, red box).
In the case of free Alexa555, a single fluorescence lifetime of 228 ps was measured, whereas encapsulated fluorophores decayed with a fluorescence lifetime of 228 ps, as well as through a second pathway with a lifetime of 1.5 ns (Fig. 4c).
Tau aggregation in GVD has been interpreted as representing a second pathway of tau aggregation [ 12].
Happiness and health are found on a second pathway as well, the cultivation of the emotions that enable us to bring out the good in others — reverence, compassion, gratitude, awe, love, and modesty.
When it does, Iran would have the ability to produce plutonium as well as enriched uranium, providing it with a second pathway to a possible nuclear weapon.
Observations of salinity, temperature and chemical-tracer data report that besides the North Pacific water, the throughflow has a second pathway as water through an eastern route of Maluku to Seram to the Banda Sea, mainly as a deep throughflow (Gordon and Fine 1996; van Aken et al. 2009).
JNK (c-Jun N-terminal kinase) is a possible candidate for such a third pathway, as there are indications that LTβR stimulation leads to activation of JNK.
A cellular mechanism such as DNA replication might also constitute a second pathway for generating the intermediate substrate of the recombination, in addition of being required for the final HJ resolution step.
