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As a first hint of allosteric networks throughout these proteases, the binding of an activated peptidomimetic inhibitor caused a structural change in the variant protease that reverted it to a wild type conformation.
However, if a significant portion of genetically modified fish developed edema, the phenotype can only be interpreted as a first hint that the kidney is affected due to multiple causes of fluid accumulation in one or more cavities of the body.
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A first hint of AS involvement in pathogenicity was given by mere comparison of average AS rates.
A first hint as to the possible mechanisms underlying the up-regulation of p130Cas/BCAR1 in tamoxifen-resistant cells comes from the analysis of the BCAR1 gene promoter.
Besides that, only one earlier study dealt with a signaling event in H. jecorina: Mach and coworkers [ 14] showed that calmodulin-antagonists interfere with xylanase formation and secretion and thereby provided a first hint as to the significance of Ca2+ signaling in this fungus.
This was a first hint that the experience gained as a system integrator was crucial for iPLON's technology of foolishness.
As the levels of 1183 mRNA were decreased at elevated levels of RNA-2571 (Fig 2B), these pilot studies provided a first hint for antisense regulation in a hyperthermophile.
Here's a third hint.
But O'Neill didn't lead a party whose base demanded that he shut down the government unless Reagan revoked his tax cuts, and O'Neill didn't face a caucus prepared to depose him as speaker at the first hint of compromise.
These frictions begin anew each year, as the first hint of spring nudges bar patrons to head outside and neighbors to open windows, according to data from the city's Department of Information Technology and Telecommunications.
As a reminder, Apple first hinted at Sonos support back in June.
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CEO of Professional Science Editing for Scientists @ prosciediting.com