Sentence examples for as a first active from inspiring English sources

They conclusively outlined strategies to discover and apply such compounds for biomedical use, resulting in the development of 9-β d-arabinofuranosyladenosine (ara-A) as a first active pharmaceutical ingredient (Müller et al. 1977).

In addition we identify a distinct set of residues unique to Thg1 that we predict as comprising a second active site, which catalyzes the initial adenylation reaction to prime 3'-5' polymerization.

The hydroxyl group of Ser70 interacts with the carbonyl of the β-lactam ring, as does a second active site water molecule (W2) that is involved in hydrolysis of the acylated enzyme.

As the Recovery Program achieved milestones, a fifth active release site in Sierra de San Pedro Mártir National Park, Baja California, Mexico, was added to the three release sites in California (Big Sur, Pinnacles National Park and Bitter Creek National Wildlife Refuge) and the Vermilion Cliffs release site in Arizona.

Its toxicity profile allows addition of a third active drug such as 5-fluorouracil.

The formation of such bonds would inevitably inhibit enzyme activity as the first active site is required to accept electrons from the substrate protein (Sevier and Kaiser, 2006).

If Collins never gets to do that, Buzinski added, his status as the first active male athlete to come out would fall away — "like a wedding that's canceled at the last minute".

The Brazilian Network for Continuous GPS Monitoring (RBMC) was established in 1996 by the Brazilian Institute of Geography and Statistics (IBGE) as the first active geodetic control in South America.

This element was independently discovered by three labs as the first active miniature inverted-repeat transposable element as well as the first active DNA transposon in rice.

mPing was reported as the first active MITE in plant [ 12- 14].

AluJo appears as the first active Alu dimer, followed by AluJb.