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Oxidative stress is no longer perceived as a simple imbalance between the production and scavenging of ROS, but as a dysfunction of enzymes involved in ROS production.
So what was once vaguely described in a fit of hand-waving as "a moral defect" is now being understood in ever more sophisticated ways as a dysfunction of many different brain networks that control decision making, memory and goal setting.
According to Khushf, the 'root cause' of disease is often considered as a "dysfunction of a tissue because of pathology on a cellular or subcellular level" (quoted from Kelly [2006], 1026).
Instead of seeing depression as a dysfunction, it is a functioning phenomenon.
Instead of labeling a dry spell as a dysfunction, view it as a source of wisdom.
When discussed, they were viewed as a dysfunction or perversion if discussed at all.
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Specialists had argued that woman, known as C, had a "dysfunction of the mind" which made her unable to make decisions about treatment.
According to the dominant model, ADHD is viewed as an executive dysfunction [ 2, 3], but alternative accounts present ADHD as a motivational dysfunction [ 4], arising from altered processes within fronto-striatal circuits [ 5, 6].
Atypical depressions represented as a sexual dysfunction quite often mislead the patients to seek the consultation other than psychiatric treatment.
Republican presidential candidate Michele Bachmann has described homosexuality as "a sexual dysfunction" and her husband, Marcus, runs a Christian counselling service which, it has been claimed, teaches homosexuals to "pray away the gay".
The debate over the classification of dyspareunia as a sexual dysfunction or as a pain disorder raises the question of the comparative cognitive salience of sex and/or pain in the experience of women who report pain with intercourse.
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