The phrase "as a defining marker" is correct and usable in written English.
It can be used to indicate a characteristic or feature that serves to identify or distinguish something.
Example: "In the context of cultural studies, language often serves as a defining marker of identity."
Alternatives: "as a distinguishing feature" or "as a key indicator".
In fact, Wnt activity may be used as a marker for defining CSCs in some malignancies.
The validity of FDG-uptake as a surrogate marker for defining the OBD of everolimus is supported by our PD marker results commonly used for evaluating mTOR inhibition.
Cejka et al. [ 6] have shown that FDG uptake can be used as a surrogate marker for defining the OBD of a molecularly targeted therapy.
Areas under receiver operating characteristic curves were used to determine the feasibility of using serum miRNA concentration as a diagnostic marker for defining HCC.
The receiver operating characteristic (ROC) curve and the area under the curve (AUC) were used to determine the feasibility of using serum miRNA concentration as a diagnostic marker for defining HCC.
Epigenetic silencing of BMP2 in breast cancer has also been found to promote breast cancer progression and drug resistance, as well defining a novel prognostic marker and offering novel therapeutic opportunities [ 37].
Clinical relapses are the defining feature of MS and act as the basis for categorizing different forms of the disease, as a marker to define the disease's natural history and to measure the success of new therapies.
Afterwards, the erythrocytes were acquired in a flow cytometer and used glycophorin A expression as a marker to define forward and scatter detectors.
In fact, we propose that studying CtIP/RBBP8 expression could be used as a marker to define which cancers should be treated with chemotherapeutic agents.
Tumour suppressor genes (TSGs) were frequently inactivated through promoter hypermethylation in gastric carcinoma as well as pre-malignant gastric lesions, suggesting that promoter hypermethylation can be used as a marker to define novel TSGs and also biomarkers for early detection of gastric cancer.
