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Finally, I wonder if the acronym "NAVIGATOR" was chosen because in the past the concept of postprandial hyperglycemia as a damaging factor was represented with a "wave" (28).
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We demonstrated that TGFB1 switches its protective role as observed using in vitro studies to a damaging factor in human OA cartilage, leading to an increased expression of MMP13, possibly through SMAD-independent pathway.
"Emotional neglect" from disengaged parents is also a damaging factor for children's development, says the study.
In addition, production of reactive oxygen species is also a major damaging factor in plants exposed to salinity stress (Aggarwal et al. [2012]).
There is accumulating evidence that production of reactive oxygen species is a major damaging factor in plants exposed to different environmental stresses, including salinity (Hernandez et al. [1995]).
Therefore, the elevation of Bax was a key damaging factor in OGD/ischemic neurons.
Because calcium is a critical damaging factor in ischemic neuronal death, these calcium-binding proteins might contribute to interneuronal survival.
As such, damaging factors most often considered are a means of mechanical action of meteoric and man-made particles.
While some historians solely blame the Portuguese for the destruction of the caves, others also cite water-logging and dripping rainwater as additional damaging factors.
Airway inflammation primarily initiated as a defense process aiming to eliminate the damaging factor, which evolves to chronic state causing airway remodeling and impaired lung functions.
Hyphae penetrate tissue by a combination of physical forces exerted by the extending filaments, the secretion of hydrolytic enzymes and as yet unknown damaging factors, which finally leads to disruption of host cell membranes (Wächtler et al., 2012).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com