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The SNP genotyping was used as a crude indication of potential hemizygosity across SHANK3 within the IMGSAC multiplex families.
However, an over-representation of non-synonymous substitutions can be used as a crude indication of either adaptive evolution or at least relaxed constraint in protein-coding genes.
Similar(58)
Obviously, this information could be biased, and serves as only a crude indication for time of onset.
The findings are only a crude indication of nationwide interest in dieting.
We used a simple asset register and the number of meals eaten in a day to give a crude indication of socio-economic status.
The dN/dS values were substantially <1 in all subgroups, providing a crude indication that the strong purifying selection has been maintained across land plants (Supplementary Table S2).
A look at firms' sales as a percentage of GDP (see table) offers a cruder indication of clout.
The Conservatives deride this as a crude "core vote strategy".
As a crude cut, however, it has succeeded.
But Zelaya rejects it otherwise as a "crude maneuver".
"You can think of an artificial neural network as a crude simulation of a brain.
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CEO of Professional Science Editing for Scientists @ prosciediting.com