However, it is not known whether the alterations of MVA pathway contribute to cancer etiology or whether its dysregulation occurs as a consequence of transformation.
Little bustard populations have suffered reduction and isolation as a consequence of landscape transformations resulting from changes in traditional agricultural systems.
As seen in Figure 3A, the chemical shift of Cζ of the chromophore is shifted downfield away from the tyrosine cluster as a consequence of the chemical transformation involved in maturation that extends the conjugation.
Therefore, this study shows that most epigenetic modifications occur as primordial and essential events during the establishment of malignant transformation in this murine melanoma model, rather than as a consequence of cell transformation [ 27].
The degradation in V2O5 was accomplished by destabilization of YSZ as a consequence of depletion of yttria from the solid solution to form YVO4 and therefore led to the disruptive transformation of the metastable tetragonal phase to the monoclinic phase.
While the roles of viral gene products in the transformation process have been described in detail, whether genetic alterations are introduced as a consequence of EBV transformation is less well understood.
As a consequence of neoplastic transformation and loss of epithelial cell polarity, MUC1 molecules enter the bloodstream.
This proadhesive phenotype may be caused by a constitutive change of integrins into the active conformation as a consequence of malignant transformation.
In this study, we have found that Akt-transformed cells are sensitive to inhibition of glycolysis because, as a consequence of their transformation, they are unable to efficiently oxidize fatty acids to maintain bioenergetics.
Glycosylation changes arising as a consequence of malignant transformation influence cell growth as well as differentiation, adhesiveness and immunogenicity of cancer cells [ 15].
As a consequence of the intraglomerular transformation, these histograms are flatter than the ORN response histogram (Fig. 2 (B)).
