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As a consequence of the target definition, the regions that are likely under high LD contain all exons and their regulatory sequences including promoter regions of genes or cis-acting regulatory elements, which typically regulate gene transcription by functioning as binding sites for transcription factors.
Distinguishing between healthcare consumption and production losses as a consequence of the target disease and comorbidity is difficult, especially in psychiatric disorders, as patients also may have physical symptoms that are connected to the psychiatric illness.
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As a consequence of the MyoD suppression, some of its target genes including myogenin and m-cadherin were also downregulated (Fig. 2A).
In particular, the contribution from energetic neutrals varies as a consequence of the atomic mass of the process gas in comparison to the target material to be sputtered.
As a consequence of the loss of auto-repression, we show that elevated levels of ectopic Myc lead to an increase in Myc activation of its targets.
One such question is whether patient experiences of ED treatment has changed as a consequence of implementation of the target.
As a consequence of this situation, the target "appears" in multiple different range cells of radar echoes, so it is also called a range distributed target [2].
Another advantage is increased levels of phylogenetic information in target regions, compared to those targeted in UCE studies (A.R. Lemmon, unpub. data), as a consequence of targeting more variable regions of the genome.
· Evidence of downstream pharmacodynamic effects as a consequence of target engagement.
As a consequence, the targeting of the GBM invasion process is a major topic of interest [ 3- 5].
Inhibition of nucleic acid synthesis can also occur as a consequence of targeting other metabolic pathways.
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