As a consequence of switch-off, Tau co-aggregates undergo structural reorganization with release and clearance of exogenous Tau, whereas the aggregated endogenous mouse Tau persists for several months.
Costs incurred either in the process of switching or as a consequence of switching are thus likely to include those for administration, additional clinic visits, extra laboratory tests and possibly hospitalization due to the patient's condition not being adequately controlled by the substituted drug (e.g. for cardiovascular events associated with suboptimal blood pressure control [ 17]).
In addition, the nature of the matrix produced in the degenerate IVDs differs from that in normal IVDs, as a consequence of switches in the production of collagen within the inner annulus fibrosus (IAF), and nucleus pulposus (NP) from type II to type I [ 7] and in the synthesis of proteoglycan from aggrecan [ 8] to versican, biglycan, and decorin [ 9, 10].
The analysis of metabolic activities of UC-derived MSC in our study were in agreement with previously described increases in glucose consumption and lactate production at low oxygen tension as a consequence of switching cell metabolism from oxidative phosphorylation to anaerobic glycolysis as well as an up-regulation of the glucose transport into the cells [ 27, 30].
Resting-egg production is therefore a consequence of switching from an asexual type of reproduction to sexual reproduction.
It seems that the regulatory activity of miR-124 is completely abolished as a consequence of base switch between positions 5 and 6.
At E = 60 kV cm−1, the 103 Bragg planes of BFO underneath the electrode are rotated as a consequence of ferroelastic switching by shear strains, and consequently they no longer satisfy the Bragg condition at (varvec{q} = varvec{G}_{103}^{mathbf{BFO}}) and appear in the XDM image with dark contrast (left panel).
Plausibly, they formed from time to time as a consequence of transitory switching to an extensional stress field following total shear stress release along the low-angle thrusts.
A hidden failure is defined as a permanent, undetected defect in a protection relay that causes a relay to operate incorrectly and remove elements of the system as a consequence of another switching event in the system [25].
However this does not account for the longer duration of P. falciparum infections as a consequence of antigenic switching (Molineaux et al., 2001), and the important role of heterogeneity in exposure (Smith et al., 2005).
Indications of processes driving gall-thrips diversification acting on the K. rugosus and K. waterhousei complexes might be expressed differently in K. rodwayi and K. maslini as a consequence of host switching.
