Sentence examples for as a consequence of mutations in from inspiring English sources

Ras proteins are constitutively activated in 30% of human tumors, including lung cancer tumors, as a consequence of mutations in ras genes.

However, the dysregulation of TFE3 or TFEB as a consequence of mutations in other tumor suppressor genes has not been reported.

Cancerous cells arise as a consequence of mutations in the critical genes.

This may indicate that BimS expression is lost during melanoma development as a consequence of mutations in B-RAF.

Computational simulations suggested increased flexibility throughout the protein structure as a consequence of mutations in the intracellular domain.

These results further strengthen the idea that plant resistance to rapamycin evolved as a consequence of mutations in plant FKBP proteins.

As species diverge, satDNAs accumulate changes as a consequence of mutations and turnover mechanisms in separate lineages generating species-specific satDNA arrays (Dover 1986).

Deregulations of kinases as a consequence of mutations as well as over- or underexpression can cause abnormal changes in cellular signaling and, as a consequence, have implications for the progression of diseases such as cancer, diabetes and inflammation [1].

Gene expression can be altered as a consequence of mutations or epigenetic changes.

Loss of function of p53 as a consequence of mutation has been shown in 50% of human cancers [ 3].

Deregulated ERK1/2 signalling drives many human cancers as a consequence of mutation or overexpression of proteins downstream in this oncogenic pathway.