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The heterogeneity of NBS clusters has been discussed and interpreted as a consequence of evolutionary events such as ectopic recombination, chromosomal translocation and gene-cluster remobilization.
Based on the results of epistasis analyses, we proposed that the SA-signaling pathway in rice branches into WRKY45-dependent and OsNPR1-dependent sub-pathways as a consequence of evolutionary divergence between rice and Arabidopsis [ 19, 30].
Briefly, early developmental stages are usually extremely well conserved, whereas adult phenotypes vary as a consequence of evolutionary divergence, a classical observation made by early developmental biologists [ 23, 24].
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It has been hypothesized that the snake venom gland itself evolved in the mouth region as a consequence of an evolutionary change in the pancreatic trait, and consequently, some of the toxins should show strong affinities to pancreatic proteins [ 1].
Science makes this understandable as a consequence of the evolutionary enlargement of the human brain; females of other animals do not experience this difficulty.
The healthcare system faces various challenges in human immunodeficiency virus (HIV) therapy due to resistance to Anti-Retroviral Therapy (ART) as a consequence of the evolutionary process.
By contrast, these isoprene compounds are synthesized through the MEP pathway in plastids of plants as a consequence of the evolutionary relationship of plastids to cyanobacteria.
Perhaps as a consequence of these evolutionary paradigms, a fundamental sex difference exists in the utilization of carbohydrates and lipids as fuel sources (Fig. 2).
We therefore conclude that these distinct sub-types evolved as a consequence of alternative evolutionary histories in response to non-photosynthetic pressures.
The molecular ecology literature offers ample evidence that these different diversity units are often also ecologically different as a consequence of their evolutionary divergence [e.g. [ 26- 28]].
We therefore conclude that these different sub-types evolved as a consequence of alternative evolutionary histories in leaf development, rather than biochemical or photosynthetic pressures.
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