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In addition, Mps1-inhibited yeast cells were found to display spindle morphology defects and chromosome mispositioning [6], possibly as a consequence of errors in chromosome biorientation [13].
In this present work we show that such mutations do arise spontaneously in vivo, most likely as a consequence of errors in replicating DNA damaged by reactive oxygen species.
However, in the typical cell, the main NMD substrates are probably abnormal transcripts that acquired PTCs as a consequence of errors during transcription or pre-mRNA processing (He et al, 1993; Jaillon et al, 2008; Sayani et al, 2008).
Like most diseases, EC arises as a consequence of errors occurring in the cellular regulatory system or errors being introduced into the genome as mutations causing cellular behavior to deviate from the norm [ 4].
Accounts trying to explain the involvement of the ANS in error processing have not always provided clear explanations of the role of the ANS engagement as a consequence of errors.
Such OR-related interpretations of error-related ANS activity have been provided already in the 1970s of the twentieth century (Danev and de Winter 1971), but have not been followed up on in later studies demonstrating ANS activity as a consequence of errors.
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As early as in 1971, heart rate has been shown to decelerate as a consequence of error commission (Danev and de Winter 1971).
The majority of low-frequency drug resistance-related mutations detected using NGS are most likely due to errors inherent in the NGS method or as a consequence of error-prone HIV-1 replication, thus clinicians prescribing ART should interpret such findings with considerable caution.
Some mutations appear spontaneously as a consequence of replication errors, error-prone repair of DNA lesions provoked by endogenous factors (e.g. metabolites or reactive oxygen species) and unequal segregation of chromosomes during mitosis (even in cells not exposed to any genotoxic stress conditions).
It occurs as a consequence of transmission errors, timing problems in analog-to-digital conversion, or damaged pixel elements in image sensors [1].
Adverse drug events (ADE) occur as a consequence of medication errors or as adverse drug reactions (ADR).
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