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All the gaps were treated as a complete deletion.
The NJ tree was constructed using MEGA 4.1, and Maximum Composite Likelihood distance [ 47] was used and gaps were treated as a complete deletion.
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Analysis of French Neutropenia registry data revealed chronic familial neutropenia in seven families predisposing to MDS/AML associated with GATA2 mutations that included a complete deletion of GATA2 locus as well as additional mutations (p.R396Q, R204X, R330X, E224X, A372T, and M388V) 64.
As shown in Figure 5(A), the mutant version rescued a complete deletion of the rpn12 + gene as well as WT.
As an example, the alternative transcript with a complete deletion of exon 2 results in a 260-aa protein variant where the arginine 26 changes to glutamine.
As indicated in Figure 1, deletion of exon 14 leads to a complete deletion of codon V617, a hot spot for mutation in patients with non-CML MPNs [3], [4].
The million-SNP array indicated a complete deletion of about a third of both copies of a gene known to be involved in the digestion of certain starches.
"We see a complete deletion of the infectious version of the malaria parasite," James said in the press release.
Genotyping demonstrated a complete deletion of the endogenous murine frataxin gene for each clone, hereafter referred as hFXN, hFXNG130V and hFXNI154F clones (Fig. 2B).
A complete deletion of the gap and missing data information was applied.
Trees were rooted at midpoint, using a complete deletion or pairwise deletion, the Poisson correction option, and 500 bootstrap replicates.
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