Similarly, we explored a complementary outcome to early GFR loss (i.e., development of CKD stage 3 [or greater]).
We also consider as a complementary secondary outcome a change in categorical diagnoses in which we seek to determine the number of persons who shift to none to minimal diagnostic category at 4 months.
Similarly, a recent review highlighted that few studies had investigated the relationship between subjective and objective QoL assessment, concluding that researchers ought to use both approaches as complementary outcome measures in schizophrenia [ 14].
Thus, the biocrystallisation method seems to be a promising complementary outcome measure for plant bioassays investigating effects of homeopathic preparations.
The Close Kinetic Chain Upper Extremity Stability Test (CKCUES test) is a low cost shoulder functional test that could be considered as a complementary and objective clinical outcome for shoulder performance evaluation.
It is possible that more effective chemotherapy may, in turn, increase the chance of offering surgical management as a complementary treatment and with improved outcome; in that context also, the place of transplantation for children with HEHE may be reconsidered in the future.
The development of a serum biomarker that can be applied simply and easily in clinical practice as a complementary tool for the prediction of prognostic outcome would be a welcome addition in the LC setting.
