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We identified these stretches of residues based on our low-resolution (18 Å) cryo-EM reconstructions, and thus as a coarse approximation to the actual physical interface.
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The width of the burst was thus 13 samples or 65ms and its waveform was a coarse approximation to a Gaussian.
This is however just a coarse approximation.
This is of course a coarse approximation to reality.
For heterogeneous refractive index cells, it is possible to use a coarse approximation on the cell refractive index [ 4].
However, describing an individual's health with a small number of discrete states is a coarse approximation because human physiology is complex and continuous in nature.
That said, this class of model's representation of health by a limited number of discrete health states and rigidly defined annual event cycles remains a coarse approximation.
SPG is particularly well suited to large-scale problems because it builds a coarse approximation efficiently and without any memory overhead.
The physical simulation uses a volume mesh comprised of quadratic tetrahedra, which are constructed from a coarser approximation of the detailed surface.
This initial polygon can be considered as a very coarse approximation to the final surface.
A z-coordinate is also available, which is defined as the maximum of the width and height of the object and can be used as a (very) coarse approximation of distance.
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Justyna Jupowicz-Kozak
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