The group with severe leukopenia presented ARDS onset more frequently and needed artificial ventilation or inotrope support (P<0.001).
However, all infants received the same routine treatment including inhalations with nebulised racemic epinephrine and none of the infants needed artificial ventilation.
In the Netherlands, a 16-year-old girl with spinal muscular atrophy type II (wheelchair-bound and needing artificial ventilation) sought treatment at a hospital for an infected wound on her right foot thought to be caused by an insect bite (online Appendix Figure, www.cdc.gov/EID/content/17/6/1137-appF.htm).
Late complications was essentially ICUAP intensice care unit acquired pneumoniae 60% in Group «T» and 68% in Group «I» p = 0.405, wich had increased the need of artificial ventilation by 6 days in Group «T» and 10 days in Group «I».
The PSI has been validated in this study, accurately predicting mortality and the need for artificial ventilation.
Using PSI < 91 for predicting absence of the need for artificial ventilation, specificity of 100% and sensitivity of 91% were demonstrated.
The severity of the respiratory involvement varies from mild symptoms to the need for artificial ventilation for several months [ 7, 13].
In addition mortality, oxygenation index (arterial pO2/inspiratory O2 fraction: PaO2/FiO2) need of artificial ventilation and inflammatory markers (CRP, white blood count, temperature) were investigated.
Patients with SAH in good or reasonable clinical condition (World Federation of Neurological Surgeons grades 1 to 3) were mostly admitted to the MCU; patients in poorer condition (World Federation of Neurological Surgeons grade 4 or 5) were admitted to the ICU, as were patients in need of artificial ventilation or inotropic support.
First-line therapy (before and during transport) consisted of artificial ventilation, fluid resuscitation, vasopressors, if needed, and i.v. infusion of 10% ethylalcohol as an antidote.
