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The results support the hypothesis that artificial modulation of propriospinal neuron excitability may facilitate recovery of motor function after spinal cord injury.
Indeed, the scheme is equivalent to an artificial modulation of the length of the BEC trap, which can be implemented by a modulation of the atomic interaction strength [8, 9].
As LY30 is derived from LY29, we were interested to see whether artificial modulation of Hsp27 protein expression could affect the outcome of TRAIL and/or LY30 treatment.
In all studies performed in various species so far artificial modulation of Pex11 levels has resulted in variations in peroxisome size and abundance; deletion of the PEX11 gene invariably leads to fewer enlarged organelles, whereas PEX11 overexpression leads to an increased number of smaller and often tubulated peroxisomes.
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Summing up, artificial epigenomic modulation of in vitro cultured MSCs using the nonspecific HDAC inhibitor, designated as TSA, seems to facilitate much more the reprogramming process for epigenetically determined transcriptional activity of somatic cell-inherited nuclear genome in the NT pig embryos.
This article also reviews artificial ECMs used for modulation of stem cell behaviors for tissue engineering applications.
Nanolaminates can be: one-dimensional, i.e. an artificial crystal with a composition modulation of amorphous layers; two-dimensional with one component layer crystalline; or three-dimensional wherein all the layers are nanocrystalline.
Controlled drug release through nanovalves, molecular electronics, artificial molecular muscles, information storage, and modulation of surface properties are topics of active research in this area.
Modulation of the ACT-induced solute efflux by cholesterol content was reported in artificial membranes [11].
Platforms for the scalable, tunable, and simple modulation of transcription would enable new abilities to study natural systems and implement artificial capabilities in living cells.
A possible alternative to such RNA-targeting approaches is the modulation of gene expression at the transcriptional level, by using zinc-finger (ZF -based artificial transcription factors (ZF -basedthartificialtranscription desired DNA target sequence.
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