To date there has not been an intra-articular combination therapy available for relief of knee osteoarthritis symptoms – one that combines the fast acting onset of symptom relief provided by a corticosteroid with the long-lasting symptom relief provided by HA in a single injection.
In conclusion, intra-articular bupivacaine in combination with intravenous parecoxib improved pain relief and reduced the demand for rescue analgesics in patients undergoing total knee arthroplasty.
In view of this, we hypothesized that intra-articular bupivacaine in combination with intravenous parecoxib may improve postoperative pain relief in patients undergoing total knee arthroplasty.
Intra-articular bupivacaine in combination with intravenous parecoxib may improve pain relief and reduce the demand for rescue analgesics in patients undergoing total knee arthroplasty.
In addition, our results indicated that patients receiving intra-articular bupivacaine in combination with intravenous parecoxib consumed significantly less meperidine than patients receiving intravenous parecoxib postoperatively in the first 24-hour observation period.
Our experience has clearly revealed heterogeneity within each class — a multi-fragmentary articular and metaphyseal group (combination of 41C2 and 41C3) is not uncommon and often the most difficult to treat (Fig. 2).
In order to promote cell growth and circumvent cellular dedifferentiation, we evaluated the effects of Transforming Growth Factor Beta-2 (TGF-β2), Insulin-like Growth Factor-I (IGF-I) and basic Fibroblast Growth Factor (bFGF) combination on articular chondrocytes culture and 'chondrocytes-fibrin' construct formation.
This combination of articular cartilage repair tissue, plus a new shock absorber, did the trick, permitting the high-level athletes to return to athletic activity after years of avoiding it.
Osteoarthritis (OA) involves destruction of articular cartilage by a combination of mechanical injury, inflammatory mediators and proteolytic enzyme activity.
The aim of this study was to assess the effects of the treatment with oral glucosamine and risedronate alone or in combination on articular cartilage, synovial membrane and subchondral bone in an experimental rabbit model of OA.
This is a case series of 11 children and adolescents who underwent femoral lengthening and percutaneous hip arthrodesis using a method of extra-articular joint compression in combination with callotasis.
