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The test articles were administered on day 4 because the incidence of nausea and vomiting is higher in the first few days of schizonticidal therapy and this was given regardless of parasite clearance.
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The test article, was administered daily by gavage to male and female rats at dose levels of 0, 50, 100, 200 mg/kg/day.
This event, a loose bowel movement, occurred on the day the test article was administered and resolved the following day without the need for concomitant medication.
Of 189 articles reviewed, 27 validated instruments were administered in 26 unique trials, with a mean of 1.9 instruments (median: 1; range: 1 7) per trial.
References in retrieved articles were reviewed to identify trials in which biologics alone were administered.
Doses were administered by nurses.
Questionnaires were administered physically.
These drugs were administered intravenously.
Analgesics were administered as required.
Endless procedures and pills were administered.
Drugs were administered intraperitoneally (i.p).
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