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The schemes were: Mechanical Diagnosis and Treatment (MDT, McKenzie) [ 42, 43] (7 articles), Treatment Based Classification (TBC, Delitto) [ 11] (16 articles); Pathoanatomic Classification (PBC, Petersen) [ 12] (2 articles); Movement System Impairment Classification (MSI, Sahrmann) [ 44] (7 articles); and the O'Sullivan Classification System (OCS) [ 45] (7 articles).
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It consisted of one test article treatment group of ten male and ten female Sprague Dawley rats dosed with [19F]FTC-146 at 0.069 mg/kg, equivalent to 250× the anticipated clinical dose mass.
However, these changes did not appear to be related to the test article treatment since they were still within the limits of normal biological variation.
In many articles, various treatment methods were introduced to rehabilitate esthetics and oral health of the patients with CCD, which includes prosthetic treatment with fixed prosthesis or partial denture regardless of the presence of impacted teeth.
Four of the articles investigated treatment response [12, 15, 18, 47].
Of all the cost estimates in the articles (76 treatment costs), 21 were based on studies that included fewer than 150 patients.
Articles about treatment of drug addiction and drug addiction in patients with mental illnesses were also excluded.
A manual review of references from each pertinent article, review articles, and treatment guidelines was also conducted to identify additional related articles.
Of those 11 that fulfilled the criteria, computer management systems were studied in four articles and treatment protocols in 11 articles.
In all, 32% (16) of articles included treatment as a variable in univariable or multivariable analyses, or as stratification in the multivariable model.
In two articles (three treatment groups) subjects were randomly assigned to groups [ 30, 31] and in one article the groups were randomly assigned but the subjects were not [ 29].
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